Ah I see you have the main problem using legacy controls. Here are some tips to help.

When using skills auto face enemy. Make sure this is enabled. At GL 3 you have less than 2.5 seconds to skill. You auto attacl every 3 ish to 4 seconds. Every skill will help with an auto attack.

Next get used to toggling lock on in between escaping AoEs and attacking. While locked on you will always be facing enemies so you will lose no damage.

Finally when fighting large monsters where lock on is an issue. After a skill simply hit w or up and face towards the monster to allow the auto attack. This will sometimes lose damage if your reflexes arent good.