I tried the 1234567890-= to buttons method, and although I like it, especially for DPS ( less frantic on blm, the cast times lets you choose your next action button without rush)

I strugle a bit with the same config while healing as SCH though. Guess it comes with practice?

It's just that I have been a keyboard gamer for years (FFXI) and WoW (binded my extra needs to the numpad).

I'm still faster on keyboard ( for now!) but the mouse does not cramp my fingers in the awkward CTRL/SHIFT combos.