Titan is a mild gear check for all classes but more importantly is a BIG awareness check.

IMHO Turn One is easier than Titan in terms of execution. You will need two decently geared tanks, healers on their game, and someone capable of bringing a target down to sub 10% hp without killing it reliably. If you have those things you can kill Caduceus.

If people cannot live through Titan they are completely screwed on Turn Two (ADS).