I macro Misery's End onto Heavy Shot because it only affects the last 20% of the battle. However I keep Bloodletter separate. I prefer the control to react to it separately rather than having to mash the one button and wait for animation. I play with controller so I have one macro for all the buffs to save some room (I have a horizontal bar below the cross bar with all the macroed skills so i can see the individual CD. I also macro Internal Release in front of both bites (on separate buttons) as it has the fastest CD and I particularily want the crit boost on the dots for RoB procs.

Apart from that I only have macro for Blunt Arrow with a line for /p chat to indicate I have silenced for things like ADS. When I don't need to use communicate i switch the macro for the plain skill to weave inbetween GCD