Click target through the party window. Once you start casting you are free to change targets, move the party window near your character so you can see when to dodge and watch health/debuffs at the same time. The best hotkeys are often overlooked, its the mouse scroll, it eliminates the need to spam a button and is so easy to use, unfortunately FF14 doesn't let you map mouse scroll so you have to progam your mouse to use keyboard inputs (I use -=). I have cure (MS up), regen (MS down), cure II (MS shift + up), medica (MS shift + down), sprint (M3), then I use the side buttons on my razor naga mouse for cooldowns/esuna, I use 234 for damage spells and click holy/cleric stance. I also make a vertical hotbar and set it to the left of the party window, I put cure II and cureIII (for the rare click heal) there so you can easily see when your free casts proc, I also put revive there and click it if needed. I use WASD to move and hold right click to steer with the camera.