One of main problems with Titan is nothing in this game prepares you for it. There are so many people hitting up relic quest like its "go kill 5 mice" type deal and getting to Titan because the entire chain of quests is a laughable 1 night joke of activities. I considering Demon Wall to be the most difficult boss throughout the entire relic quest prior to Titan and that is -only- because of the mechanics. You have to move a lot, you can end up fighting in a small space and you can fall to your death with Demon Wall helping to achieve that with repel to knock you off, very similar mechanics to Titan, small area, Aoe's to dodge, knock back moves and a ledge to fall off. All other fights are weak. Then Titan hits and its a whole other level compared to what you've gone through.

The only advice I can give to secure a win is learn his rotation and do your actions and movement in advance, pretend plumes are already up when you "know" they are about to be up, and get moving.