My setup uses two cross action bars bars and one extra hotbar. The cross action bars both have all healing spells, aetherflow, and energy drain on the right side so I always have access to them. The left of the first bar is defensive cd and utility spells and manual embrace. The second bar has all dps spells(all macros) on the left. The extra hotbar has both fairy summons, limitbreak, a macro to set my focus to my targets target, swiftcast and surecast(macros), and some non combat abilities (return, teleport, etc).

The macros I use are as follow: Set my focus to my targets target (generally the tanks target). Summons with swiftcast.. Resurrect with swiftcast. Virus and all dps spells cast on my focus and my target if I have no focus.
I always set my focus to the boss so I can see his casts bar but can still freely heal the party. Same goes for why I macro to attack my focus. Some may prefer to just attack their targets target in their macros.

I do no pet management besides manual embrace (turned pet bar off) but could add place if needed. I generally only manual embrace when the situation calls for it. Otherwise I leave eos to herself and she does perfectly fine.