Depends on the debuff being thrown around. Debuffs such as Paralyze, Reduced Movement Speed, or Reduced Healing Effects should be removed on the tank first, then yourself, then any dps.
As for Medica it depends on how much it heals and how much you feel comfortable with leaving the party's HP at. You mention using it on Titan at 57-70% HP, is that enough to top people off, or keep them at a safe amount for the next big AE that hits? If you feel comfortable, make no changes, but if you aren't comfortable with leaving people a little low on health, you may want to reconsider using other options.


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