The biggest problem so far is how SE decides to tackle these problems with botters and rmts, instead of addressing the issue of how reporting, investigation and suspension can be improved, or simply accepting the fact that people are going to cheat, and rmts are going to make money, they simply end up hurting the players that invest the time into this or that.
like right now, gatherers hit a 50% sp fatigue after a couple of hours, add the actual sp fatigue system on to this, and even at stage 1 you're losing 55% of your sp gain, and you aren't getting any items either

imagine if they made it so that after 200 synths you broke everything and received half sp for the synth
or you killed 200 monsters and now you get no drops, and your sp is halved

sound fair?
ya, i didn't think so