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Is there really no better way to get these in 4.4? The new Infusion potions use them now and imo the quantity obtainable with Botany/Mining ephemerals just isn't enough to really cover needs. These sand were designed for gear creation not expendable potions...
The Grade 2 Infusions used Dawnlight Aethersands and the Grade 1 Infusions used Dusklight Aethersands. It was easy enough to navigate around the time gating on both by spearfishing in Ruby Sea (aetherial reduction from false scads etc gave the desired sands). But Duskglow doesn't really need that, since there's a Duskglow item in every ephemeral node.
Running 800 gp it's pretty easy to get a large quantity of sand per window. You expend 200gp at a time to let it come back, but cap out when you find a +2 (or +1 if it's being stubborn) node.
Then you do the usual collectible rotation but with 800 gp you get an extra 'Extra attempt' use. Rng swings your way and it's 6 500+ collectibles in one go.