Windows 10 - Gamepad Intermittent Loss of Response

Time: Various times daily
Frequency: Intermittent between every 10-20 minutes
World name: Excalibur
Character name: Zuenini Zueni
Class/Level: Any
Party or solo: Both
In-game time: Various
Area and coordinates: Any area both instances and world

Steps:
1. Use gamepad (Dualshock 4) normally.

2. Gamepad will lose response for 1-2 seconds and last input before loss of response will be stuck until gamepad regains response. Confirmed that gamepad issue does not occur in other games.

3. Issue seems to go away if "Microsoft Device Association Root Enumerator" is disabled in [Device Manager\Software Services] but more testing required to confirm. Issue seems to stem game client checking gamepad/joysticks for connection status when Windows adds a new device to list.

Connection Specs
- Type of internet connection/provider: ADSL

PC Specs
-=-=-=-=- System Information -=-=-=-=-

SYSTEM_OS Windows 10 Pro 64-bit (6.2, Build 9200) (14393.rs1_release.161220-1747)
SYSTEM_CPU Intel(R) Core(TM) i7-2600K CPU @ 3.40GHz (8 CPUs), ~3.4GHz
SYSTEM_CORE_NUM SYSTEM_CORE_LOGIC 8 SYSTEM_CORE_PHYSICS 4
SYSTEM_BIOS BIOS Date: 10/31/12 20:41:07 Ver: 36.02
SYSTEM_LANGUAGE English (Regional Setting: English)
SYSTEM_MEMORY 16351.137MB
SYSTEM_VIRTUAL_MEMORY 2047.875MB
SYSTEM_PAGE_FILE 32735.137MB
SYSTEM_STORAGE C:\ SYSTEM_HARDDISK_DRIVE SYSTEM_TOTALDISC_SPACE 930.589GB SYSTEM_FREEDISC_SPACE 673.095GB
SYSTEM_STORAGE D:\ SYSTEM_HARDDISK_DRIVE SYSTEM_TOTALDISC_SPACE 931.511GB SYSTEM_FREEDISC_SPACE 493.294GB
SYSTEM_STORAGE E:\ SYSTEM_HARDDISK_DRIVE SYSTEM_TOTALDISC_SPACE 3726.021GB SYSTEM_FREEDISC_SPACE 2653.984GB
SYSTEM_DIRECTX_VERSION DirectX 12
SYSTEM_GRAPHICS NVIDIA GeForce GTX 980 Ti
SYSTEM_GRAPHICS_DEVICE \\.\DISPLAY1
SYSTEM_GRAPHICS_CHIP GeForce GTX 980 Ti
SYSTEM_GRAPHICS_MAKER NVIDIA
SYSTEM_GRAPHICS_VRAM 3072.000 MB
SYSTEM_GRAPHICS_SHARED_VRAM 1023.938 MB
SYSTEM_GRAPHICS_DAC Integrated RAMDAC
SYSTEM_GRAPHICS_DISPLAY_MODE 1920 x 1200 (32 bit) (59Hz)
SYSTEM_GRAPHICS_DRIVER C:\WINDOWS\System32\DriverStore\FileRepository\nv_dispi.inf_amd64_02838dee03d82b94\nvd3dumx.dll,C:\WINDOWS\System32\DriverStore\FileRepository\nv_dispi.inf_amd64_02838dee03d82b94\nvwgf2umx.dll,C:\WINDOWS\System32\DriverStore\FileRepository\nv_dispi.inf_amd64_02838dee03d82b94\nvwgf2umx.dll,C:\WINDOWS\System32\DriverStore\FileRepository\nv_dispi.inf_amd64_02838dee03d82b94\nvwgf2umx.dll
SYSTEM_GRAPHICS_DRIVER_VERSION 21.21.0013.7849
SYSTEM_GRAPHICS_DRIVER_DATE 1/19/2017 16:00:00
SYSTEM_GRAPHICS_DRIVER_LANGUAGE English
3.0
SYSTEM_GRAPHICS_PIXEL_SHADER 3.0
SYSTEM_GRAPHICS_VERTEX_TEXTURE SYSTEM_SUPPORT
SYSTEM_SOUND Speakers (Realtek High Definition Audio)
SYSTEM_SOUND_DEVICE_ID {7351815A-1321-4DB7-BF33-ED4FE0D8489E}
SYSTEM_SOUND_DEVICE_NAME RTKVHD64.sys
SYSTEM_SOUND_DRIVER_VERSION 6.00.0001.7848
SYSTEM_SOUND_DRIVER_LANGUAGE English
SYSTEM_SOUND_DRIVER_DATE 6/14/2016 00:00:00
SYSTEM_SOUND Speakers (Corsair Vengeance 1500)
SYSTEM_SOUND_DEVICE_ID {5603A4B0-5A13-4C51-A098-379194F1D51A}
SYSTEM_SOUND_DEVICE_NAME CAHS164.sys
SYSTEM_SOUND_DRIVER_VERSION 7.00.0008.2150
SYSTEM_SOUND_DRIVER_LANGUAGE English
SYSTEM_SOUND_DRIVER_DATE 6/16/2011 00:00:00
SYSTEM_SOUND Realtek Digital Output (Realtek High Definition Audio)
SYSTEM_SOUND_DEVICE_ID {862E9829-7691-46C2-8953-C72255FBDDF3}
SYSTEM_SOUND_DEVICE_NAME RTKVHD64.sys
SYSTEM_SOUND_DRIVER_VERSION 6.00.0001.7848
SYSTEM_SOUND_DRIVER_LANGUAGE English
SYSTEM_SOUND_DRIVER_DATE 6/14/2016 00:00:00
SYSTEM_SOUND Realtek Digital Output(Optical) (Realtek High Definition Audio)
SYSTEM_SOUND_DEVICE_ID {A2DCE1A0-9DD1-4843-9293-928B7D46132E}
SYSTEM_SOUND_DEVICE_NAME RTKVHD64.sys
SYSTEM_SOUND_DRIVER_VERSION 6.00.0001.7848
SYSTEM_SOUND_DRIVER_LANGUAGE English
SYSTEM_SOUND_DRIVER_DATE 6/14/2016 00:00:00
SYSTEM_SOUND Headset Earphone (4- DUALSHOCK®4 USB Wireless Adaptor)
SYSTEM_SOUND_DEVICE_ID {A60655D8-0BC6-4F68-A578-309652218923}
SYSTEM_SOUND_DEVICE_NAME USBAUDIO.sys
SYSTEM_SOUND_DRIVER_VERSION 6.02.14393.0000
SYSTEM_SOUND_DRIVER_LANGUAGE English
SYSTEM_SOUND_DRIVER_DATE 7/15/2016 00:00:00
SYSTEM_INPUT {6F1D2B60-D5A0-11CF-BFC7444553540000}
SYSTEM_INPUT_NAME Mouse
SYSTEM_INPUT_REMARKS SYSTEM_GAMEPAD_AXIS 3 SYSTEM_GAMEPAD_BUTTON 8 SYSTEM_GAMEPAD_FOV 0
SYSTEM_INPUT {6F1D2B61-D5A0-11CF-BFC7444553540000}
SYSTEM_INPUT_NAME Keyboard
SYSTEM_INPUT_REMARKS SYSTEM_GAMEPAD_AXIS 0 SYSTEM_GAMEPAD_BUTTON 128 SYSTEM_GAMEPAD_FOV 0
SYSTEM_INPUT {FC334EC0-9928-11E4-8001444553540000}
SYSTEM_INPUT_NAME Gaming Keyboard G910
SYSTEM_INPUT_REMARKS SYSTEM_GAMEPAD_AXIS 0 SYSTEM_GAMEPAD_BUTTON 7 SYSTEM_GAMEPAD_FOV 0
SYSTEM_INPUT {FC3375D0-9928-11E4-8002444553540000}
SYSTEM_INPUT_NAME Gaming Keyboard G910
SYSTEM_INPUT_REMARKS SYSTEM_GAMEPAD_AXIS 0 SYSTEM_GAMEPAD_BUTTON 0 SYSTEM_GAMEPAD_FOV 0
SYSTEM_INPUT {FC3375D0-9928-11E4-8003444553540000}
SYSTEM_INPUT_NAME Gaming Keyboard G910
SYSTEM_INPUT_REMARKS SYSTEM_GAMEPAD_AXIS 0 SYSTEM_GAMEPAD_BUTTON 0 SYSTEM_GAMEPAD_FOV 0
SYSTEM_INPUT {9D605F20-F90C-11E4-8003444553540000}
SYSTEM_INPUT_NAME Saitek Pro Flight X-55 Rhino Stick
SYSTEM_INPUT_REMARKS SYSTEM_GAMEPAD_AXIS 0 SYSTEM_GAMEPAD_BUTTON 0 SYSTEM_GAMEPAD_FOV 0
SYSTEM_INPUT {925DA7C0-76AC-11E2-8001444553540000}
SYSTEM_INPUT_NAME Corsair Vengeance 1500
SYSTEM_INPUT_REMARKS SYSTEM_GAMEPAD_AXIS 1 SYSTEM_GAMEPAD_BUTTON 5 SYSTEM_GAMEPAD_FOV 0
SYSTEM_INPUT {790BE010-967C-11E4-8001444553540000}
SYSTEM_INPUT_NAME Gaming Mouse G502
SYSTEM_INPUT_REMARKS SYSTEM_GAMEPAD_AXIS 0 SYSTEM_GAMEPAD_BUTTON 652 SYSTEM_GAMEPAD_FOV 0
SYSTEM_INPUT {95A8A9E0-F90C-11E4-8001444553540000}
SYSTEM_INPUT_NAME Saitek Pro Flight X-55 Rhino Throttle
SYSTEM_INPUT_REMARKS SYSTEM_GAMEPAD_AXIS 0 SYSTEM_GAMEPAD_BUTTON 0 SYSTEM_GAMEPAD_FOV 0
SYSTEM_INPUT {790C0720-967C-11E4-8002444553540000}
SYSTEM_INPUT_NAME Gaming Mouse G502
SYSTEM_INPUT_REMARKS SYSTEM_GAMEPAD_AXIS 0 SYSTEM_GAMEPAD_BUTTON 3 SYSTEM_GAMEPAD_FOV 0
SYSTEM_INPUT {73D2E890-D888-11E2-8001444553540000}
SYSTEM_INPUT_NAME Controller (XBOX 360 For Windows)
SYSTEM_INPUT_REMARKS SYSTEM_GAMEPAD_AXIS 5 SYSTEM_GAMEPAD_BUTTON 10 SYSTEM_GAMEPAD_FOV 1
SYSTEM_INPUT {790C2E30-967C-11E4-8003444553540000}
SYSTEM_INPUT_NAME Gaming Mouse G502
SYSTEM_INPUT_REMARKS SYSTEM_GAMEPAD_AXIS 0 SYSTEM_GAMEPAD_BUTTON 0 SYSTEM_GAMEPAD_FOV 0
SYSTEM_INPUT {9826A230-F90C-11E4-8002444553540000}
SYSTEM_INPUT_NAME Saitek Pro Flight X-55 Rhino Throttle
SYSTEM_INPUT_REMARKS SYSTEM_GAMEPAD_AXIS 8 SYSTEM_GAMEPAD_BUTTON 35 SYSTEM_GAMEPAD_FOV 0
SYSTEM_INPUT {790C2E30-967C-11E4-8004444553540000}
SYSTEM_INPUT_NAME Gaming Mouse G502
SYSTEM_INPUT_REMARKS SYSTEM_GAMEPAD_AXIS 0 SYSTEM_GAMEPAD_BUTTON 0 SYSTEM_GAMEPAD_FOV 0
SYSTEM_INPUT {32232030-6A22-11E0-8002444553540000}
SYSTEM_INPUT_NAME Programmable Hotkeys
SYSTEM_INPUT_REMARKS SYSTEM_GAMEPAD_AXIS 0 SYSTEM_GAMEPAD_BUTTON 669 SYSTEM_GAMEPAD_FOV 0
SYSTEM_INPUT {A206B5B0-F90C-11E4-8004444553540000}
SYSTEM_INPUT_NAME Saitek Pro Flight X-55 Rhino Stick
SYSTEM_INPUT_REMARKS SYSTEM_GAMEPAD_AXIS 3 SYSTEM_GAMEPAD_BUTTON 17 SYSTEM_GAMEPAD_FOV 1
SYSTEM_INPUT {C1302720-FA9F-11E4-8001444553540000}
SYSTEM_INPUT_NAME Saitek Pro Flight Combat Rudder Pedals
SYSTEM_INPUT_REMARKS SYSTEM_GAMEPAD_AXIS 3 SYSTEM_GAMEPAD_BUTTON 0 SYSTEM_GAMEPAD_FOV 0

-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-

Sony Dualshock 4
Gamepad Manufacturer: Sony
Gamepad Model Name: Model CUH-ZCT1U

Happens with Microsoft Xbox One controller as well.

Disable "Microsoft Device Association Root Enumerator" under Software Devices in Windows' Device Manager. Worked like a charm for me when my Xbox One controller had this issue.