cast a spell while auto-running does not force the character to stop and cast
Time: Always
Frequency: Everytime
World name: All
Character name: Any
NPC name: N/A
Monster name: N/A
Class/Level: All
Party or solo: Both
In-game time: Always
Area and coordinates: All
Steps:
1. Turn on autorun
2. Cast teleport or return
According to the 3.01 patch notes: An issue wherein attempting to cast a spell while auto-running would not force the character to stop and cast the spell.
This does not seem to be the case.