Will we have the option of a PC-like setup on FFXIV for PS4?

A Realm Reborn supports mouse and keyboard on PS3, but the options are limited and you still have to use the cross hotbar. This is most likely due to the fact that there is considerably less real estate on screen for PS3 because the resolution is lower and everything takes up more room.

If SE are able to get the game running at 1080p on PS4 do you think we will see a fully customisable UI more in line with what PC users have access too for those that want to use M/K?

It's actually a memory limitation on the PS3. But I don't doubt SE would be able to have it for PS4, since there won't be a memory limitation.

I think Reinheart had a translation game watch interview with Yoshida and in it Yoshida makes mention that the ps4 will be 98% like pc.