To be honest, I think you can make good profit outside of uldah, but your probably better off sticking to expendables, like crafting materials, crafting/gathering tools designed for the town, and arrows and such. If I'm in Gridiana and I ever bought any crafting material, I be more likly to buy logs there or at least check there before heading to Uldah. Or if I'm doing leve's in Gridiana I be looking there for arrows and stuff.
I go to grid for cheap shards on Lindbulm. I haven't seen LL markets in a while. last I remember it was full of retainers selling sheep skin for 20,000 a piece or something.
Yeah I have had a hard time selling finished items as of late regardless of + quality. though +quality materials have sold like candy. Like buffalo straps +3's those went quick for 400,000 a piece XD.
i personally dislike grindanina. But i do almost all of my shopping in limsa and put my retainers there.
I can say i started up in Limsa but ultimatly i have my char parked up in Ul'dah exclusivly for the daily leve quests with my friends ,i end up going to limsa ussaly if im on for longer durations tho i do prefure the city layout and designs would love a reason to set up shop and stay there tho!