https://media0.giphy.com/media/mywys...giphy.gif&ct=g
As an option? Sure, why not.
Mandatory for everyone? This late into the game's life, it would be very jarring.
I probably wouldn't notice or care to be honest, it isn't something I pay any attention to. Most of the time my WoL seems to just be referred to as "my friend" "our champion" "hero" w/e else. Pretty sure the Scions don't even know her name.
They use your name plenty when it's not voiced. There's no way they could voice every single possibility for a player name. (And, considering some of the things people will name their characters, there's plenty of reason they wouldn't want to.)
I don't want american politics in my game so I will unsubscribe harder than ever.
The last time pronouns came up I was in favor of expanding the list and letting you pick regardless of gender, but forcing one set on everyone is something that would annoy me.
I would quit the game asap