Originally Posted by
Enkidoh
in that specific reference to humorism the game itself even states that in universe it's possibly load of bunk with the description for the chigoe larva minion (which also revealed what a chirgueon actually is - it's not a fantasy name for a surgeon, but a quack doctor that uses a blood-sucking parasite to drain small amounts of blood from the patient to supposedly drain 'dark humors', in this case, a chigoe); that far from helping the patient it was discovered that the patients were contracting additional diseases and problems as a result!
The word' 'leech' also seems to be used in a similar manner - a 1.0 main story quest used that term to refer to a doctor when seeking medical treatment, and there is of course the SCH spell 'Leeches'. So yeah, the game kinda zigzags whether humorism really does work or if it's just a convinent way of explaining something coincidental in medical terms that has a more mundane, scientific explanation.