SC>Infuriate>w/e shouldn't be possible because you shouldn't be building 5 Wrath before the adds pop. If you are, for whatever reason, you're doing it under the effect of Unchained and in that case you already used your Infuriate.
The best start is: pre-build HS on boss -> Defiance -> Infuriate -> SS add #1 -> BB add #2 -> Veng/Thrill -> SC -> Defiance off -> OP -> apply SE to Daughter -> BB -> SE -> etc etc
400+ basically requires near max STR and an i130-i135 wep (easier with i135). Sometimes mechanics can get in the way and murder your DPS, but that's rare since most mechanics have you hitting the boss at the same time anyway.
You can also completely cheese your DPS and stack adds but I wouldn't recommend that unless you're in for a lot of learning.
Best example I can give is Xeno: http://www.twitch.tv/xenosysvex/c/6101176
There's a lot of factors to account for, like how short the encounter is, how much uptime you get on Fracture, etc. etc. T10 is kinda wonky to judge your DPS on.
