Sadly, the enormous cooldowns on potions, coupled with their brief duration, means that this is not really so. Anyone who wishes to take advantage of 5-hit nodes likely wants to do it over and over again during a single gathering session. Potion cooldowns mean they can only take advantage of the 5-hit node once every five minutes (or 4 min, 30 seconds for HQ). A gatherer rotating between nodes will come back to that 5-hit node WAY more often than that, so the actual benefits are pretty minimal.
