I actually do have modifiers (regular hotbar, CTRL hotbar, ALT hotbar) and I have one of those MMO mice (worth it). The only issue is I tend to use buttons 1-8 because those are the only ones I can reliably reach with my thumb with any form of comfort/accuracy.
I also have a hotbar with clickable stuff that isn't bound to any keys. Honestly, if I cared more, I would train my thumb to use the other keys, but it gets uncomfortable. Thanks for the suggestion, though.
And your numbers on Foresight are interesting. I'll be the first to admit that part of the reason I macro'd it to Shadowskin is because it felt like something to pop just to pop it. You're going to make me actually take it more seriously!
