I would definitely like the next story arc to just be the Scions dealing with more local problems and exploring the world, instead of dealing with world or universe ending threats.
Especially considering the threat we just defeated is the incarnation of nihilistic apocalypse. Like what else would there be left after that?
Otherwise the story will start to suffer big time. It's the issue WoW has faced, after WOTLK they had to dig deeper into fluff lore to find villains and it went off the rails becoming bad since they delayed fighting the villain setup by Warcraft 2 for 4 expansions instead filling with with stuff from the appendixes of the Warcraft 3 manual. Then after that its just nonsense. The MCU is dealing with it too because nobodies gonna be able to really live up to Thanos and as well acted as Kang is he's a bit too comical. Really comic books in general have a huge issue with it. The Star Wars sequels suffered this as well both in its old EU books and the new movies. A ton of animes that go on for too long have this issue as well, which is why the more well regarded series tend to run for at most 200 episodes and the kino stuff is 25-60 episode series.