GTX 460 and 296.10 (Maybe other cards as well?)
After installing 296.10 the game became very unstable for me, barely able to play more than five minutes. Rolled back to 295.73 and I was good to go. I see a lot of other NVIDIA posts and wonder if this might not help. Also if any of the mods see this they should put in a word with NVIDIA to get this remedied for the next release.
UPDATE
Installed the new 301.24 beta drivers and ran for hours with no issues last night. In fact NVIDIA was boasting a 5-20% performance improvement on a bunch of games so I beefed up the quality a bit even.