What is the dot pitch and native resolution of that 46" monitor? And the dot pitch/size of the other systems' monitors? That is what I am talking about with the stretching. If there is a large enough gap between the pixels, you may be more prone to see the stair-stepping because of the bigger gaps. A 46" with 3840/2160 actual pixels will render naturally like a 23" at 1920/1080--same size pixels. But if you stretch it to full screen, then you are stretching the pixels. Likewise, if it has anything less than 3840/2160 actual pixels, then each dot is bigger and thus it is getting stretched--same number of pixels are rendered, but each pixel is larger then it is on a 23" with 1920/1080 pixels. Going from around 100 dots per inch to around 50 gives you a bigger pixel to look at, so any imperfections would be more pronounced. Essentially, it is the same analogy of holding the newspaper closer.

The game's output is the same across all systems--but it is rendered differently on each screen. If all the screens of those systems you are talking about have roughly the same pixel count and gaps between pixels, then they will all likely have the same issues at the same resolutions (or relative ratios to size/DPI differences).

As I stated ealier... the ones with a resolution rendering the game around the 96 DPI range (likely the size of the font) don't appear to be seeing this issue.