AF4

[Karbuncle]

This is true, I myself have been looking on where to cut down on my sets depending on situations. But, its not always so easy & clear cut, for instance I have these as my sets.

I can try provide some help to that.

Melee
TP
TP Accuracy
TP PDT
Death Blossom
Requiescat
Frontline Cures(Basically Self cures for when fighting up close)

Here, I'd remove Mercy Stroke, Chant, and Knights of Round gear, as they are all tied to now useless weapons. Thanks SE , I've stopped using my Mandau all together on THF and RDM as its not worth it anymore, the new weapons are too powerful.

Personally I'd pick a weapon and use it, at this point, You'll want sword since SE Forgot RDM can wield dagger apparently, and the Delve Swords are far better than any dagger we can touch, So if you're bringing a Melee set, There's the narrowed version.

Magic
Backline Cures
Composure Buff(For spells like Haste which Composure duration helps without effecting potency)
Enhancing
Fast Cast
MND Enfeebling Accuracy
MND Enfeebling Potency
INT Enfeebling Accuracy
INT Enfeebling Potency
Nuking

I don't think you can remove much here, However you can likely drop the Potency Sets in Delve, as most NMs you'll want the Accuracy. however if you have GEO buffs/Debuffs, Can ditch the Acc and go with the potency. (So long as your POtency Builds obv have a healthy dose of M.acc, Which most will, and yOU have Capped Enfeebling+Merits)

Other
Physical Damage Taken
Magical Damage Taken
Refresh(Basically has almost all situational Refresh pieces)
Refresh Damage Taken

I'd say you can consolidate Refresh and RefreshDT into one set. Add the 5 Refresh pieces most people use (5 visible slots), and Fill the other slots with the PDT. Personally something like Earth Staff, Twilight Torque, 2x 6% Dark Rings, Umbral Cape, Flume Belt, and a (1) PDT-2% Earring will bring you at 49% PDT at Daytime, and Capped PDT at Night. If you have a Dring You're at 48% Daytime, 50% Night, and you still get to use all 5 Visible Refresh pieces, and Even a slot for a WoTG Earring. If you don't have a WoTG Refresh Earring, You can use 2 PDT-2% Earrings and be at 50% in night or Day, all while keeping your Refresh Set on.

for Visual Reference

No D-ring. 1 PDT Earring.
Earth Staff -20%
Twilight T. -5%
6%Drk Ring x2 - 12%
Umbra cape -6%
Flume Belt -4%
PDT-2%Ear -2% (dur)
*Total - 49% In the Day, Overcapped at night.

Dring.
Earth Staff -20%
Dring - 10%
t.Torque -5%
Umbra/Flume - 10%
PDT-5% Drk Ring -%
*Total = -50%

If you have a Dring, Could even settl for an NQ Umbra Cape (Cheviot) with a PDT-6% Ring and a -2%/-1% Earring. (Colossus' Earring is -1%, Easy from Alexander fight). This is all while leaving your Head, Body, Hands, Legs, and Feet free for Refresh pieces.

So, I've only really managed to Cut off a few pieces of gear for you , But I know your pain.