The market will be good initially, but you'll be looking at needing at least 45 Honey, Sage, and Distilled Water, and crystals. I don't believe people farming Honey or crystals will match up, and from the server I'm on that's about 416g per Honey while the NPC cost of Sage is around 166g. Throw in the water and the crystal at 150g and you're looking at 732g per synth. Building a stack of 99 will run you 32,940g at 45 synths. More realistically, I'm going to say you'll need 60 synths to do it, so that becomes 43,920g. Keep in mind there are NPCs that effectively ceiling the value of Echo Drops (~832g). The AH cost may exceed them from time to time, but when that number goes too far past, people will either divert to the NPCs or you'll get people buying from the NPC and relisting to make their own money for nothing.
In general, the medicine market is terribly volatile when it comes to Echo Drops, Silent Oil, and Prism Powder. It only takes one person to start a spree of undercuts. We're past the days of ToAU where imps are one of the EXP mobs of choice. People will not be chugging Echo Drops in the extreme that once you get past the initial post-patch sales, you'll be seeing more than a couple stacks a day selling. When things start selling slow, people start getting more willing to unload at a cheaper price just to recover their investment. At 10k for a stack of 12, a drop is a whopping 13g profit. Do you see people willing to pay 85k or more for a stack of drops if you want at least 100g profit per? I don't. The moment that drops to under 73k, you're losing money. You'd be better off NPCing Holy Waters at like 350g per where every HQ is a guaranteed, instant profit.
Basically you'd need to triple synth yields and third NPC resale costs for the affected to put things back into reasonable time investments. Even then, profits will be paper thin.


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