When running AK I find I usually top the hate list against trash with a simple rotation:
Shadow Flare > Bio II > Miasma > Bio > Bane > Fester > Thunder > Ruin until Fester is back up
I don't know if that's optimal but it seems to work well enough
However my problem comes in boss fights. Once I get past the initial opening my DPS really seems to suffer. I'm not sure how to keep up continuous damage. I feel like I waste too much time reapplying dots too early, not sure when to use Shadow Flare or not, whether Miasma II is worth using, when to use Thunder etc. I also tend to get flustered and caught up in dodging boss mechanics and I quickly fall to 8 on the hate list
So any tips would be totally awesome